Where Data Meets Mission: A Conversation with Aptive’s Chief Medical Officer Dr. Adi Gundlapalli

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Where Data Meets Mission: A Conversation with Aptive’s Chief Medical Officer Dr. Adi Gundlapalli

Posted on 07.20.26
Man in a dark suit and glasses standing with arms crossed in front of a blue digital background showing medical imaging, including a brain scan, chest X ray and hand X ray.

There are not many people who can say they have briefed members of White House Task Forces, published research in the top 0.1% of cited scientists worldwide, led data and analytics for the national response to a global pandemic and still see patients every Tuesday. 

Adi V. Gundlapalli, M.D., Ph.D., M.S., can say all of that. But what matters more than the resume is the conviction that runs through it: a career-long belief that the value of data, technology and clinical expertise is not measured in platforms or publications, but in whether it actually makes things better for the person at the other end. 

That belief now shapes how Aptive approaches its work in federal health, and it is why the company made its first-ever appointment of a chief medical officer. 

Informatics as Science and Practice 

Dr. Gundlapalli keeps his definition of informatics deliberately simple: getting the right information to the right people at the right moment so they can make a good decision. That holds whether the setting is a clinic, a state health department or a federal surveillance operation. 

The American Medical Informatics Association defines informatics more formally as the science of how to use data, information and knowledge to improve human health and the way care is delivered. What Dr. Gundlapalli likes about that definition is its dual nature. Informatics is a scientific discipline with a rigorous foundation. It is also a living practice, something that plays out every day in a rural clinic, an urban emergency department, a federal health system or a public health surveillance operation. 

For the skeptical clinician who just wants the system to work, he has a practical test. “My test is always: how is the clinician’s day going? Did we give them time back? Did we make the safe thing the easy thing? If yes, we did our job. If not, we just have to get better.” 

That test matters because it keeps the human being at the center, not the system. A data pipeline or an electronic health record has no value on its own. It has value when a clinician can use it to make a better call for a patient without spending half a shift fighting the interface. 

On AI: Enthusiastic and Careful 

The question of where AI helps and where it gets in the way is one Dr. Gundlapalli approaches with a clear North Star: technology should give people time back to focus on the patient and the public’s health. That is the test. If a tool passes it, it belongs. If it does not, no amount of impressive demos changes the answer. 

He borrows a phrase from Abraham Verghese, an infectious disease physician and writer whose work he has followed since his fellowship days in Utah. Dr. Verghese, it turns out, graduated from the same medical school in Madras that Dr. Gundlapalli did. Dr. Verghese coined the term “iPatient” for the version of the patient that lives in the computer, receiving meticulous attention while the real person in the bed wonders where everyone went. 

AI, Dr. Gundlapalli argues, can push either direction. It can take on the work humans should not have to do by hand: finding signals in large datasets, flagging a quietly deteriorating patient overnight, lifting the documentation burden that is driving burnout across clinical and public health workforces. Or it can make the iPatient problem worse, adding another layer between the clinician and the person they are there to serve. 

“The right posture is enthusiastic and being careful at the same time. Move at an appropriate pace on the infrastructure and setup. Move carefully where human life is on the line. The race that everyone is pushing, the FOMO mentality, that does not seem healthy, nor is it sustainable. You don’t have to be first at everything. You have to get there and do it well.” 

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What Aptive Does That Others Don’t 

Dr. Gundlapalli is five months into his role at Aptive and measured about drawing broad conclusions. But one observation comes through clearly: Aptive operates where federal health modernization tends to succeed or fall apart, at the point where technology, clinical reality and program management have to work together or they do not work at all. 

“A lot of organizations can do the technology. A lot can do the consulting and management. Many can do the clinical side,” he says. “But the hard part, and the valuable part, is connecting the three, so that whatever we’re helping with actually brings value to the Veteran, to the patient, to the system.” 

That combination shows up across Aptive’s portfolio. The VA work through the Integrated Healthcare Transformation contract. The Indian Health Service work. The Joint Commission-certified clinical staffing that puts clinicians directly into underserved federal health settings. Each reflects the same idea: modernization that holds up in the real world, not just in a demo. 

What surprised him about Aptive from the inside was the depth he had not expected from the outside. “From the outside, you might see a mid-size firm,” he says. “From the inside, I see a deep bench and expertise across all the areas we want to work in, and a hunger to expand. There’s a genuine mission alignment here that I don’t think is easily manufactured.” 

What drew him to say yes to Aptive was the proximity to impact. At CDC, the distance between a decision and its effect on an individual was sometimes measured in years. At Aptive, he can watch work move from contract to execution to outcome in weeks or months, close enough to see it land. 

Data Travels at the Speed of Trust 

When Dr. Gundlapalli thinks about what will drive Aptive’s long-term success in federal health, he returns to a phrase a senior CDC leader passed along years ago: data travels at the speed of trust, not light. 

He does not measure Aptive’s ambition primarily in contract wins (although they certainly help). He measures it by whether federal agencies, when they have a hard problem, pick up the phone and call, not because Aptive is on a contract vehicle but because they trust the team to think through it with them. 

“It’s when the government stops thinking of us just as another vendor and starts thinking of us as a partner,” he says. “When they have a problem to solve and one of them calls and says, ‘Can I have half an hour? There’s something we want to brainstorm.’ That brings the pleasure and the joy. And it’s a bigger ambition than any single contract.” 

“Don’t be afraid of complexity. The most important federal health problems are really messy and span many stakeholders. That’s not a reason to avoid them. That’s exactly where the interesting work is, and where a team like ours can make a difference.” 

 

Build for the Person at the End 

When asked what single idea he would impart upon his team, Gundlapalli makes it concrete. 

Whatever you are building this week, a platform, a data pipeline, a slide deck or a proposal, picture the person at the end of it. The Veteran waiting for a result. The patient who drove an hour for an appointment. The nurse with too many tabs open. The facility director dealing with pressures that are not entirely within her control. The public health worker who spent another weekend on a data pipeline most people will never know existed. 

“Build for that patient, that person, that staff, that leader,” he says. “Give grace and keep that other person in mind. How would this help them? Would this complicate things for them? Keep that end user in mind. That’s Informatics 101. That’s Customer Service 101.” 

It is a simple test. It is also a demanding one. And it is the question he has carried across every role in his career, at VA, at CDC, in academic medicine and in the clinic every Tuesday. “Are we able to make it better for the person and the community at the other end?” 

That question is not going away. And at Aptive, it is the gold standard against which the work gets measured. 

ABOUT DR. GUNDLAPALLI

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Dr. Adi Gundlapalli is the Chief Medical Officer at Aptive. He is board certified in internal medicine, infectious diseases and clinical informatics and also holds a Ph.D. in biomedical sciences and a master’s degree in biomedical informatics. He has authored more than 200 peer-reviewed publications. In 2025, he was named a Clarivate Highly Cited Researcher, placing him among the top 0.1% of researchers worldwide for citation impact. He continues to practice medicine at Emory Healthcare in Atlanta.
Adi V. Gundlapalli, MD, PhD, MS Chief Medical Officer, Aptive